As we know that covid-19 pandemic was very challenging for healthcare workers from the beginning. Due to the crisis of covid-19, healthcare workers faced several problems treating patients with covid-19. COVID-19 has affected the life and health of more than 1 million people across the world. Exploring the issues that nurses face during their battle will help support them and develop protocols and plans to improve their preparedness. Thus, this integrative review will explore the issues facing nurses during their response to the Covid-19 crisis. Methodology: The study design was non-experimental research design. Total 200 samples were selected for data collection. A Non-probability purposive sampling technique was used to collect data from the samples. Tool was constructed to identify the demographic variables, and a set of structured questionnaires Data collection was done from staff nurses of selected hospital. Each participant was provided data collection tool. Result: 93(46.5%) of nurses rarely having face any allergic reaction or skin problems like rash, itchy skin, pressure mark or dryness due to N-95 mask. 82(41%) are rarely suffered from urinary incontinence, burning micturition for holding urine for long time during Covid-19 pandemic because of PPE kit Conclusion: The results indicated that the majority of nurses claimed that employment during the COVID-19 crisis had a little influence on the physical and mental wellbeing. they having some problem like anxiety of new diseases, long standing work hours, dehydration, N 95 mask marks .But by the time they are positively deal with the Covid 19 situation.

(Assess, Effect, Covid 19, Exposure, Physical Emotional health).