Selection of binders and their concentration is very important in the formulation of tablet. For better result, it is very essential to choose appropriate binder at suitable concentration. To study the effect of binders at different amount on drug release, disintegration and hardness of tablet. In order to accomplish the objective, materials viz. Guar Gum, Gum Kraya, PVK K30 as binders and drug aceclofenac as a model drug were procured and purchased. For the preparation of tablet, wet granulation method was adopted. Prepared formulation were subjected for various evaluation parameters such as precompression and postcompression parameters. From all the prepared tablets, it was found that Guar Gum at 1% w/w, Gum Karaya at 3% w/w and PVP K30 at 2% showed better result. Because of these binders have different properties. It was concluded that Guar Gum, Gum Karaya and PVP K30 can be considered as appropriate excipient as binding agent at low concentration.

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