Introduction: Stroke is a disease that affects the arteries leading to and within the brain. It is the No. 5 cause of death and a leading cause of disability in the United States. A stroke occurs when a blood vessel that carries oxygen and nutrients to the brain is either blocked by a clot or bursts (or ruptures). Stroke, cerebrovascular accident (CVA), or brain attack is the onset and persistence of neurologic dysfunction resulting from disruption of blood supply to the brain and indicates infarction rather than ischemia. Aim of the study – Aim of the study was to determine the effectiveness of structured teaching program on knowledge and practice regarding national institute of health stroke scale among third year B.BSc nursing students in selected nursing institute. methodology: This study based on quantitative research approach, (Quasi experimental study- one group pre-test post-test research design) was used . The sample size was 50 third year B.BSc Nursing students and sample technique was non probability convenient sampling technique. The data collected was analyzed by using descriptive and inferential statistics in terms of frequency, mean, standard deviation , chi square and paired ‘t’ test. Result : The study reveals that mean knowledge score 21.88 with SD 3.07 and mean percentage knowledge score was 72.93% with SD 10.24. Mean practice score was 8.88 with SD 1.82 and mean percentage practice score was 59.20% with SD 12.16. Analysis on correlation by using Pearson correlation coefficient test shows positive correlation(r = 0.970 ) between knowledge score and practice score of third year B.BSc nursing students. Conclusion : the study reveals that there is a deficit knowledge and practice regarding national institute of health stroke scale in pretest . the post test knowledge and practice was increased which reveals that structured teaching program was effective on knowledge and practice regarding national institute of health stroke scale

Effectiveness ,Stroke, National institute of health stroke scale, Health, Brain.